The disc cutter is one of the main components of TBM tunneling in hard rock; therefore, the wear of the cutting disc in TBM tunneling has a major impact on the performance of the tunneling machine, its productivity and tunneling costs. The study of cutting disc wear, especially considering the effect of operating parameters, has made the prediction of disc consumption a difficult task. The main objective of this study is to investigate the effect of operating parameters on the wear of the cutting disc of the tunnel boring machine. The key parameters affecting the wear of the cutting disc, such as rock strength, rock abrasiveness, normal force (trust force), rolling force and rotation speed (rpm) of the disc, are investigated. The expected results of the parametric study include understanding the degree of impact of operating parameters on cutting disc wear for various types of rocks and selected disc cutters. Finally, a comparison is made between the results of cutting disc wear measured by the full-scale testing machine with different operating parameters and their effects on disc wear are determined.